磁共振成像（MRI）是用于低渗透神经肌肉疾病临床评估的非侵入性工具。自动诊断方法可能会减少对活检的需求，并提供有关疾病随访的宝贵信息。在本文中，提出了三种方法，以根据胶原蛋白VI相关的肌病病例对目标肌肉进行分类，这些方法是根据它们的参与程度（尤其是卷积神经网络），一个完全连接的网络来对纹理特征进行分类，并结合了两种特征套。对26名受试者的轴向T1加权涡轮自旋Echo MRI进行了评估，其中包括乌拉里奇先天性肌肉营养不良症和伯特莱姆肌病患者在不同的进化阶段。对于健康，轻度和中度/严重的病例，混合模型的全球精度分别为93.8％，其全球精度分别为0.99、0.82和0.95，获得了最佳的交叉验证结果。

Model estimates obtained from traditional subspace identification methods may be subject to significant variance. This elevated variance is aggravated in the cases of large models or of a limited sample size. Common solutions to reduce the effect of variance are regularized estimators, shrinkage estimators and Bayesian estimation. In the current work we investigate the latter two solutions, which have not yet been applied to subspace identification. Our experimental results show that our proposed estimators may reduce the estimation risk up to $40\%$ of that of traditional subspace methods.

Stress has a great effect on people's lives that can not be understated. While it can be good, since it helps humans to adapt to new and different situations, it can also be harmful when not dealt with properly, leading to chronic stress. The objective of this paper is developing a stress monitoring solution, that can be used in real life, while being able to tackle this challenge in a positive way. The SMILE data set was provided to team Anxolotl, and all it was needed was to develop a robust model. We developed a supervised learning model for classification in Python, presenting the final result of 64.1% in accuracy and a f1-score of 54.96%. The resulting solution stood the robustness test, presenting low variation between runs, which was a major point for it's possible integration in the Anxolotl app in the future.

Applying deep learning concepts from image detection and graph theory has greatly advanced protein-ligand binding affinity prediction, a challenge with enormous ramifications for both drug discovery and protein engineering. We build upon these advances by designing a novel deep learning architecture consisting of a 3-dimensional convolutional neural network utilizing channel-wise attention and two graph convolutional networks utilizing attention-based aggregation of node features. HAC-Net (Hybrid Attention-Based Convolutional Neural Network) obtains state-of-the-art results on the PDBbind v.2016 core set, the most widely recognized benchmark in the field. We extensively assess the generalizability of our model using multiple train-test splits, each of which maximizes differences between either protein structures, protein sequences, or ligand extended-connectivity fingerprints. Furthermore, we perform 10-fold cross-validation with a similarity cutoff between SMILES strings of ligands in the training and test sets, and also evaluate the performance of HAC-Net on lower-quality data. We envision that this model can be extended to a broad range of supervised learning problems related to structure-based biomolecular property prediction. All of our software is available as open source at https://github.com/gregory-kyro/HAC-Net/.

Dataset scaling, also known as normalization, is an essential preprocessing step in a machine learning pipeline. It is aimed at adjusting attributes scales in a way that they all vary within the same range. This transformation is known to improve the performance of classification models, but there are several scaling techniques to choose from, and this choice is not generally done carefully. In this paper, we execute a broad experiment comparing the impact of 5 scaling techniques on the performances of 20 classification algorithms among monolithic and ensemble models, applying them to 82 publicly available datasets with varying imbalance ratios. Results show that the choice of scaling technique matters for classification performance, and the performance difference between the best and the worst scaling technique is relevant and statistically significant in most cases. They also indicate that choosing an inadequate technique can be more detrimental to classification performance than not scaling the data at all. We also show how the performance variation of an ensemble model, considering different scaling techniques, tends to be dictated by that of its base model. Finally, we discuss the relationship between a model's sensitivity to the choice of scaling technique and its performance and provide insights into its applicability on different model deployment scenarios. Full results and source code for the experiments in this paper are available in a GitHub repository.\footnote{https://github.com/amorimlb/scaling\_matters}

Human motion prediction is a complex task as it involves forecasting variables over time on a graph of connected sensors. This is especially true in the case of few-shot learning, where we strive to forecast motion sequences for previously unseen actions based on only a few examples. Despite this, almost all related approaches for few-shot motion prediction do not incorporate the underlying graph, while it is a common component in classical motion prediction. Furthermore, state-of-the-art methods for few-shot motion prediction are restricted to motion tasks with a fixed output space meaning these tasks are all limited to the same sensor graph. In this work, we propose to extend recent works on few-shot time-series forecasting with heterogeneous attributes with graph neural networks to introduce the first few-shot motion approach that explicitly incorporates the spatial graph while also generalizing across motion tasks with heterogeneous sensors. In our experiments on motion tasks with heterogeneous sensors, we demonstrate significant performance improvements with lifts from 10.4% up to 39.3% compared to best state-of-the-art models. Moreover, we show that our model can perform on par with the best approach so far when evaluating on tasks with a fixed output space while maintaining two magnitudes fewer parameters.

Video segmentation consists of a frame-by-frame selection process of meaningful areas related to foreground moving objects. Some applications include traffic monitoring, human tracking, action recognition, efficient video surveillance, and anomaly detection. In these applications, it is not rare to face challenges such as abrupt changes in weather conditions, illumination issues, shadows, subtle dynamic background motions, and also camouflage effects. In this work, we address such shortcomings by proposing a novel deep learning video segmentation approach that incorporates residual information into the foreground detection learning process. The main goal is to provide a method capable of generating an accurate foreground detection given a grayscale video. Experiments conducted on the Change Detection 2014 and on the private dataset PetrobrasROUTES from Petrobras support the effectiveness of the proposed approach concerning some state-of-the-art video segmentation techniques, with overall F-measures of $\mathbf{0.9535}$ and $\mathbf{0.9636}$ in the Change Detection 2014 and PetrobrasROUTES datasets, respectively. Such a result places the proposed technique amongst the top 3 state-of-the-art video segmentation methods, besides comprising approximately seven times less parameters than its top one counterpart.

Scene change detection is an image processing problem related to partitioning pixels of a digital image into foreground and background regions. Mostly, visual knowledge-based computer intelligent systems, like traffic monitoring, video surveillance, and anomaly detection, need to use change detection techniques. Amongst the most prominent detection methods, there are the learning-based ones, which besides sharing similar training and testing protocols, differ from each other in terms of their architecture design strategies. Such architecture design directly impacts on the quality of the detection results, and also in the device resources capacity, like memory. In this work, we propose a novel Multiscale Cascade Residual Convolutional Neural Network that integrates multiscale processing strategy through a Residual Processing Module, with a Segmentation Convolutional Neural Network. Experiments conducted on two different datasets support the effectiveness of the proposed approach, achieving average overall $\boldsymbol{F\text{-}measure}$ results of $\boldsymbol{0.9622}$ and $\boldsymbol{0.9664}$ over Change Detection 2014 and PetrobrasROUTES datasets respectively, besides comprising approximately eight times fewer parameters. Such obtained results place the proposed technique amongst the top four state-of-the-art scene change detection methods.

Research on remote sensing image classification significantly impacts essential human routine tasks such as urban planning and agriculture. Nowadays, the rapid advance in technology and the availability of many high-quality remote sensing images create a demand for reliable automation methods. The current paper proposes two novel deep learning-based architectures for image classification purposes, i.e., the Discriminant Deep Image Prior Network and the Discriminant Deep Image Prior Network+, which combine Deep Image Prior and Triplet Networks learning strategies. Experiments conducted over three well-known public remote sensing image datasets achieved state-of-the-art results, evidencing the effectiveness of using deep image priors for remote sensing image classification.

We address the problem of integrating data from multiple observational and interventional studies to eventually compute counterfactuals in structural causal models. We derive a likelihood characterisation for the overall data that leads us to extend a previous EM-based algorithm from the case of a single study to that of multiple ones. The new algorithm learns to approximate the (unidentifiability) region of model parameters from such mixed data sources. On this basis, it delivers interval approximations to counterfactual results, which collapse to points in the identifiable case. The algorithm is very general, it works on semi-Markovian models with discrete variables and can compute any counterfactual. Moreover, it automatically determines if a problem is feasible (the parameter region being nonempty), which is a necessary step not to yield incorrect results. Systematic numerical experiments show the effectiveness and accuracy of the algorithm, while hinting at the benefits of integrating heterogeneous data to get informative bounds in case of unidentifiability.